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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salazar, David | SS | Cincinnati Roses | 23 | 10/15/2000 | San Pedro de Macorís | DOM | Left | Right | 5' 10" | 175 lbs | $780,000 |
| Sanchez, Orlando | SP | Toledo Sailors | 24 | 09/06/1999 | Guaynabo | PUR | Right | Right | 6' 4" | 205 lbs | $780,000 |
| Sanders, Brian | RP | Syracuse Oranges | 34 | 07/07/1989 | Warwick | USA | Right | Right | 6' 1" | 205 lbs | - |
| Sargent, Joey | C | Norfolk Prairie Dogs | 29 | 06/22/1994 | Brookfield | USA | Right | Right | 6' 0" | 200 lbs | - |
| Sarrano, Faical | RP | Syracuse Oranges | 31 | 12/21/1992 | Maracaibo | VEN | Left | Left | 5' 10" | 200 lbs | - |
| Sawyer, Ken | LF | Toledo Sailors | 25 | 08/28/1998 | Huntsville | USA | Right | Right | 6' 4" | 200 lbs | - |
| Schaff, Wilber | SS | Cincinnati Roses | 22 | 09/03/2001 | Beaverton | USA | Right | Right | 6' 2" | 195 lbs | - |
| Schweitzer, Ryan | SS | Syracuse Oranges | 27 | 06/28/1996 | Saguenay | CAN | Right | Right | 5' 9" | 185 lbs | - |
| Scott, Darrel | RP | Buffalo Petes | 29 | 06/16/1994 | Riverview | USA | Left | Right | 6' 6" | 220 lbs | $2,760,000 |
| Serrano, Luis | CF | Durham Redbirds | 25 | 12/01/1998 | Puerto Plata | DOM | Right | Right | 6' 4" | 205 lbs | - |
| Sharp, John | C | Norfolk Prairie Dogs | 27 | 05/22/1996 | Norwalk | USA | Left | Right | 6' 0" | 195 lbs | - |
| Sharpe, Corey | SP | Buffalo Petes | 28 | 10/25/1995 | Sparks | USA | Left | Right | 6' 4" | 210 lbs | $780,000 |
| Sheppard, Ken | RP | Scranton WB Shamans | 29 | 03/26/1995 | Niles | USA | Right | Right | 6' 4" | 200 lbs | - |
| Sheppard, Randy | SP | Durham Redbirds | 26 | 04/18/1998 | Middletown | USA | Right | Right | 6' 4" | 205 lbs | - |
| Sierra, Cisco | C | Pawtucket Sailfish | 27 | 07/04/1996 | San Juan | PUR | Right | Right | 6' 0" | 200 lbs | - |
| Silva, Armando | CL | Gwinnett Fightin Whites | 27 | 12/21/1996 | Culver City | USA | Right | Right | 6' 1" | 200 lbs | $780,000 |
| Silva, Wilfred | SP | Pawtucket Sailfish | 25 | 04/07/1999 | Staunton | USA | Left | Right | 6' 2" | 205 lbs | - |
| Simmons, Douglas | 1B | Rochester Buckaroos | 24 | 11/11/1999 | Cimarron Hills | USA | Right | Right | 6' 4" | 205 lbs | - |
| Simon, Garrett | C | Cincinnati Roses | 24 | 06/08/1999 | Cincinnati | USA | Right | Right | 6' 1" | 200 lbs | $780,000 |
| Simons, Bill | RP | Pawtucket Sailfish | 24 | 05/23/1999 | Philadelphia | USA | Left | Left | 6' 6" | 200 lbs | $780,000 |
| Sims, Joe | SP | Cincinnati Roses | 24 | 08/03/1999 | Austin | USA | Right | Right | 6' 3" | 200 lbs | $780,000 |
| Sinclair, Jack | RF | Buffalo Petes | 32 | 04/24/1992 | San Marcos | USA | Right | Right | 6' 0" | 195 lbs | - |
| Smith, Brian | 3B | Scranton WB Shamans | 30 | 12/08/1993 | Cahaba Heights | USA | Right | Right | 6' 2" | 220 lbs | - |
| Smith, J.J. | 3B | Rochester Buckaroos | 30 | 02/01/1994 | Newburgh | USA | Right | Right | 5' 10" | 195 lbs | $780,000 |
| Snow, Lou | SP | Buffalo Petes | 23 | 09/18/2000 | Denver | USA | Right | Right | 6' 7" | 205 lbs | $780,000 |
| Soliz, Francisco | RF | Rochester Buckaroos | 21 | 06/14/2002 | El Puerto | DOM | Right | Left | 6' 3" | 200 lbs | $780,000 |
| Soto, Freddy | RP | Norfolk Prairie Dogs | 25 | 11/10/1998 | Santo Domingo | DOM | Right | Right | 6' 1" | 185 lbs | - |
| Stark, Chris | RP | Scranton WB Shamans | 33 | 03/28/1991 | Los Angeles | USA | Right | Right | 6' 3" | 210 lbs | - |
| Stephens, Elmer | CL | Scranton WB Shamans | 23 | 09/03/2000 | Riverhead | USA | Left | Left | 6' 2" | 200 lbs | $780,000 |
| Stirzacre, Terry | RF | Indianapolis Valley Cats | 27 | 02/22/1997 | Seattle | USA | Left | Left | 6' 1" | 200 lbs | - |
| Strickland, Arthur | 2B | Scranton WB Shamans | 29 | 03/06/1995 | Cleveland | USA | Right | Right | 5' 11" | 195 lbs | - |
| Strickland, Willie | RP | Toledo Sailors | 34 | 11/13/1989 | Mesa | USA | Left | Right | 5' 9" | 195 lbs | - |
| Stroud, Jason | CF | Free Agent | 27 | 08/27/1996 | Bethesda | USA | Right | Right | 6' 1" | 195 lbs | - |
| Stryffler, Steve | SP | Indianapolis Valley Cats | 33 | 11/07/1990 | Santiago | DOM | Right | Right | 6' 0" | 200 lbs | - |
| Sullivan, Ezra | SS | Pawtucket Sailfish | 31 | 03/01/1993 | Sacramento | USA | Right | Right | 6' 1" | 200 lbs | $1,760,000 |
| Sullivan, Ryan | RP | Lehigh Valley Sunchasers | 26 | 09/27/1997 | Hudson | USA | Right | Right | 6' 3" | 200 lbs | $1,600,000 |
| Sullivan, Thurman | RP | Cincinnati Roses | 26 | 06/26/1997 | Jesup | USA | Left | Left | 6' 1" | 200 lbs | $780,000 |
| Summerville, Matt | SP | Lehigh Valley Sunchasers | 33 | 06/02/1990 | Baton Rouge | USA | Left | Right | 6' 1" | 205 lbs | - |
| Swanson, Nick | CF | Toledo Sailors | 23 | 06/09/2000 | Colorado Springs | USA | Right | Right | 6' 1" | 190 lbs | - |
| Swynford, Gregory | RF | Cincinnati Roses | 23 | 10/31/2000 | Denton | USA | Left | Left | 6' 1" | 195 lbs | - |
| Sánchez, Gustavo | RP | Rochester Buckaroos | 28 | 03/27/1996 | Cativa | PAN | Switch | Left | 6' 2" | 185 lbs | - |
