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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Santana, Jorge | RP | Mobile Red Ants | 24 | 07/10/1999 | San Miguelito | PAN | Left | Left | 6' 0" | 185 lbs | - |
| Santos, Felix | SP | Star City Stars | 28 | 11/06/1995 | Glen Cove | USA | Left | Left | 6' 0" | 200 lbs | - |
| Saunders, Johnny | CF | Mobile Red Ants | 30 | 09/28/1993 | Pasadena | USA | Switch | Right | 6' 0" | 195 lbs | - |
| Segura, Fernando | SP | Pensacola Diamond | 24 | 12/29/1999 | Camargo | MEX | Left | Left | 6' 2" | 190 lbs | - |
| Sheehan, Matt | 2B | Mobile Red Ants | 27 | 05/02/1997 | Fayetteville | USA | Left | Right | 6' 4" | 215 lbs | - |
| Sherman, Roy | 1B | Montgomery Thugs | 24 | 01/19/2000 | Jackson | USA | Right | Right | 5' 10" | 180 lbs | - |
| Simmons, Chad | CF | Mississippi Bandicoots | 25 | 08/20/1998 | Suisun City | USA | Left | Left | 6' 3" | 200 lbs | - |
| Sinclair, Warren | SP | Chattanooga Rowdies | 26 | 06/16/1997 | Brookline | USA | Right | Right | 6' 2" | 200 lbs | - |
| Sinski, Gus | C | Montgomery Thugs | 31 | 11/26/1992 | Los Angeles | USA | Right | Right | 6' 4" | 250 lbs | - |
| Smith, Jimmy | 3B | Birmingham Rams | 24 | 12/14/1999 | Bridgeview | USA | Right | Right | 6' 2" | 200 lbs | - |
| Smith, Nick | 2B | Tennessee Daredevils | 23 | 10/11/2000 | Fredericksburg | USA | Right | Right | 6' 0" | 185 lbs | $780,000 |
| Smith, Seth | CF | Mississippi Bandicoots | 23 | 04/21/2001 | Hot Springs | USA | Left | Right | 6' 3" | 200 lbs | - |
| Smith, Vincent | SP | Chattanooga Rowdies | 27 | 12/20/1996 | Marksville | USA | Right | Right | 6' 2" | 205 lbs | $780,000 |
| Soto, Jose | RP | Pensacola Diamond | 28 | 05/21/1995 | Guaynabo | PUR | Right | Right | 6' 4" | 200 lbs | - |
| Souza, Joseph | C | Free Agent | 28 | 04/22/1996 | Griswold | USA | Left | Right | 6' 4" | 230 lbs | - |
| Souza, Luis | RP | Birmingham Rams | 21 | 06/21/2002 | La Romana | DOM | Left | Left | 6' 4" | 190 lbs | - |
| Stevens, Robert | SS | Birmingham Rams | 21 | 12/12/2002 | Perry | USA | Right | Right | 6' 1" | 185 lbs | - |
| Sutton, Kevin | SP | Jackson Desert Sharks | 23 | 05/23/2000 | Honolulu | USA | Right | Right | 6' 4" | 200 lbs | - |
| Sánchez, Raúl | SP | Mobile Red Ants | 25 | 03/27/1999 | Higüey | DOM | Switch | Right | 6' 1" | 195 lbs | - |
