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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salinas, José | SS | Johnson City Thugs | 19 | 09/23/2002 | Ciudad Bolívar | VEN | Right | Right | 6' 3" | 185 lbs | - |
| Sánchez, Félix | RP | Burlington Wolves | 21 | 12/04/2000 | South River | USA | Right | Right | 6' 2" | 180 lbs | - |
| Sánchez, Jack | CL | Burlington Wolves | 20 | 09/28/2001 | Milwaukee | USA | Left | Left | 6' 1" | 180 lbs | - |
| Sanchez, Jorge | C | Free Agent | 24 | 03/11/1997 | Barahona | DOM | Right | Right | 6' 0" | 200 lbs | - |
| Sánchez, Júlio | RP | Danville Jesters | 21 | 10/21/2000 | Santo Domingo | DOM | Right | Right | 6' 1" | 175 lbs | - |
| Sánchez, Octávio | RP | Danville Jesters | 21 | 07/18/2000 | Higüey | DOM | Left | Left | 6' 3" | 180 lbs | - |
| Santana, Félix | CF | Burlington Wolves | 20 | 01/14/2002 | Santo Domingo | DOM | Left | Left | 6' 3" | 190 lbs | - |
| Santos, Jorge | RP | Danville Jesters | 20 | 04/19/2001 | Barahona | DOM | Right | Right | 6' 6" | 200 lbs | - |
| Saucedo, Jesús | RP | Free Agent | 29 | 04/19/1992 | San Pedro de Macorís | DOM | Switch | Right | 6' 0" | 205 lbs | - |
| Saunders, Jimmy | RP | Danville Jesters | 22 | 12/25/1999 | Ontario | USA | Left | Right | 6' 0" | 175 lbs | - |
| Scott, Dave | 2B | Free Agent | 25 | 03/13/1996 | Mt. Pleasant | USA | Right | Right | 6' 0" | 195 lbs | - |
| Sele, Gunner | SP | Elizabethton Citadelles | 20 | 06/08/2001 | Dalton Gardens | USA | Left | Left | 6' 1" | 175 lbs | - |
| Sharp, Melvin | SP | Princeton Bay Hawks | 20 | 05/30/2001 | Lorton | USA | Switch | Right | 5' 11" | 175 lbs | - |
| Silva, Albert | SS | Burlington Wolves | 21 | 08/13/2000 | Azua | DOM | Right | Right | 6' 3" | 195 lbs | - |
| Simpson, Kris | RP | Bluefield Vampires | 23 | 04/07/1998 | Ft. Hall | USA | Right | Right | 6' 3" | 200 lbs | - |
| Sims, Clancy | SP | Bluefield Vampires | 24 | 04/11/1997 | Greentown | USA | Right | Right | 6' 0" | 200 lbs | - |
| Sims, Dane | CL | Greeneville Bulldogs | 21 | 01/22/2001 | Metairie | USA | Left | Right | 5' 10" | 165 lbs | - |
| Sims, Jason | RP | Kingsport Armada | 23 | 02/17/1999 | Baldwin Park | USA | Right | Right | 6' 6" | 215 lbs | - |
| Smith, Billy | SP | Greeneville Bulldogs | 21 | 01/07/2001 | Mercerville-Hamilton Square | USA | Switch | Right | 6' 1" | 185 lbs | - |
| Soliz, Francisco | RF | Elizabethton Citadelles | 19 | 06/14/2002 | El Puerto | DOM | Right | Left | 6' 3" | 190 lbs | - |
| Souza, José | SP | Elizabethton Citadelles | 22 | 09/23/1999 | Punta Cardón | VEN | Left | Left | 5' 11" | 170 lbs | - |
| Steele, Michael | SP | Free Agent | 25 | 06/24/1996 | San Antonio | USA | Switch | Left | 6' 7" | 220 lbs | - |
| Stewart, Bobby | 2B | Bluefield Vampires | 22 | 08/07/1999 | New Brunswick | USA | Right | Right | 6' 4" | 200 lbs | - |
| Stewart, Mark | SP | Pulaski Chiefs | 20 | 08/03/2001 | Long Beach | USA | Left | Left | 6' 1" | 185 lbs | - |
| Stotzky, Max | CF | Pulaski Chiefs | 22 | 11/13/1999 | Huntington | USA | Right | Right | 6' 1" | 185 lbs | - |
