| Rank | Pitcher | Years | WAR |
|---|---|---|---|
| 1 | Walter Johnson | 1908–1927 | 144.9 |
| 2 | Roger Clemens | 1984–2007 | 134.2 |
| 3 | Greg Maddux | 1986–2008 | 112.3 |
| 4 | Lefty Grove | 1925–1941 | 111.6 |
| 5 | Pete Alexander | 1911–1930 | 111.4 |
| 6 | Tom Seaver | 1967–1986 | 103.3 |
| 7 | Randy Johnson | 1988–2009 | 102.5 |
| 8 | Warren Spahn | 1942–1965 | 97.7 |
| 9 | Gaylord Perry | 1962–1983 | 96.2 |
| 10 | Bert Blyleven | 1970–1992 | 93.0 |
| 11 | Steve Carlton | 1965–1988 | 90.3 |
| 12 | Phil Niekro | 1964–1987 | 87.1 |
| 13 | Bob Gibson | 1959–1975 | 85.9 |
| 14 | Pedro Martinez | 1992–2009 | 85.0 |
| 15 | Robin Roberts | 1948–1966 | 82.9 |
| 16 | Carl Hubbell | 1928–1943 | 82.3 |
| 17 | Justin Verlander | 2005–2025 | 80.8 |
| 18 | Mike Mussina | 1991–2008 | 80.0 |
| 19 | Clayton Kershaw | 2008–2025 | 79.7 |
| 20 | Fergie Jenkins | 1965–1983 | 78.7 |
| 21 | Tom Glavine | 1987–2008 | 78.6 |
| 22 | Curt Schilling | 1988–2007 | 78.0 |
| 23 | Nolan Ryan | 1966–1993 | 76.5 |
| 24 | John Smoltz | 1988–2009 | 74.3 |
| 25 | Don Sutton | 1966–1988 | 73.3 |
| 26 | Zack Greinke | 2004–2023 | 72.4 |
| 27 | Max Scherzer | 2008–2025 | 71.0 |
| 28 | Kevin Brown | 1986–2005 | 70.6 |
| 29 | Bob Feller | 1936–1956 | 70.5 |
| 30 | Tommy John | 1963–1989 | 70.5 |
| 31 | Red Faber | 1914–1933 | 68.5 |
| 32 | Rick Reuschel | 1972–1991 | 67.4 |
| 33 | Jim Palmer | 1965–1984 | 66.7 |
| 34 | CC Sabathia | 2001–2019 | 66.7 |
| 35 | Roy Halladay | 1998–2013 | 65.8 |
| 36 | Dazzy Vance | 1915–1935 | 65.7 |
| 37 | Ted Lyons | 1923–1946 | 65.2 |
| 38 | Don Drysdale | 1956–1969 | 64.0 |
| 39 | Andy Pettitte | 1995–2013 | 63.9 |
| 40 | Juan Marichal | 1960–1975 | 63.7 |
| 41 | Whitey Ford | 1950–1967 | 62.7 |
| 42 | Stan Coveleski | 1912–1928 | 62.6 |
| 43 | Hal Newhouser | 1939–1955 | 62.0 |
| 44 | Jerry Koosman | 1967–1985 | 61.3 |
| 45 | Red Ruffing | 1924–1947 | 60.9 |
| 46 | Jim Bunning | 1955–1971 | 60.7 |
| 47 | Eppa Rixey | 1912–1933 | 60.7 |
| 48 | Waite Hoyt | 1918–1938 | 60.1 |
| 49 | Mariano Rivera | 1995–2013 | 59.7 |
| 50 | Ed Walsh | 1908–1917 | 59.6 |
| 51 | Chris Sale | 2010–2025 | 58.5 |
| 52 | Dennis Eckersley | 1975–1998 | 58.0 |
| 53 | David Cone | 1986–2003 | 58.0 |
| 54 | Billy Pierce | 1945–1964 | 58.0 |
| 55 | Frank Tanana | 1973–1993 | 57.9 |
| 56 | Chuck Finley | 1986–2002 | 57.2 |
| 57 | Bret Saberhagen | 1984–2001 | 57.2 |
| 58 | Christy Mathewson | 1908–1916 | 56.8 |
| 59 | Larry Jackson | 1955–1968 | 56.8 |
| 60 | Tim Hudson | 1999–2015 | 56.5 |
| 61 | Mark Buehrle | 2000–2015 | 56.5 |
| 62 | Jack Quinn | 1909–1933 | 56.3 |
| 63 | Eddie Cicotte | 1908–1920 | 55.1 |
| 64 | Early Wynn | 1939–1963 | 55.0 |
| 65 | Cole Hamels | 2006–2020 | 54.4 |
| 66 | Luis Tiant | 1964–1982 | 53.4 |
| 67 | Urban Shocker | 1916–1928 | 53.1 |
| 68 | Bob Friend | 1951–1966 | 53.1 |
| 69 | Mel Harder | 1928–1947 | 52.8 |
| 70 | Sandy Koufax | 1955–1966 | 52.7 |
| 71 | Herb Pennock | 1912–1934 | 52.7 |
| 72 | Roy Oswalt | 2001–2013 | 52.1 |
| 73 | David Wells | 1987–2007 | 51.8 |
| 74 | Bob Shawkey | 1913–1927 | 51.4 |
| 75 | Felix Hernandez | 2005–2019 | 51.3 |
| 76 | Jim Kaat | 1959–1983 | 51.3 |
| 77 | Jon Lester | 2006–2021 | 51.3 |
| 78 | Bobo Newsom | 1929–1953 | 51.1 |
| 79 | Tommy Bridges | 1930–1946 | 51.0 |
| 80 | Kevin Appier | 1989–2004 | 50.5 |
| 81 | Jimmy Key | 1984–1998 | 50.4 |
| 82 | Dave Stieb | 1979–1998 | 50.4 |
| 83 | Burleigh Grimes | 1916–1934 | 50.3 |
| 84 | Dutch Leonard | 1933–1953 | 49.8 |
| 85 | Dwight Gooden | 1984–2000 | 49.8 |
| 86 | Lefty Gomez | 1930–1943 | 49.7 |
| 87 | Paul Derringer | 1931–1945 | 49.7 |
| 88 | Dolf Luque | 1914–1935 | 49.4 |
| 89 | Carl Mays | 1915–1929 | 49.4 |
| 90 | Hoyt Wilhelm | 1952–1972 | 49.3 |
| 91 | Mickey Lolich | 1963–1979 | 48.9 |
| 92 | Jack Morris | 1977–1994 | 48.8 |
| 93 | Wilbur Cooper | 1912–1926 | 48.7 |
| 94 | Bartolo Colon | 1997–2018 | 48.7 |
| 95 | Dennis Martinez | 1976–1998 | 48.6 |
| 96 | Ron Guidry | 1975–1988 | 48.5 |
| 97 | Babe Adams | 1909–1926 | 48.5 |
| 98 | Adam Wainwright | 2005–2023 | 48.4 |
| 99 | Frank Viola | 1982–1996 | 48.2 |
| 100 | Larry French | 1929–1942 | 48.1 |
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