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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salas, Armando | SP | Hickory Crazies | 27 | 02/16/1997 | Hostos | DOM | Switch | Right | 5' 9" | 175 lbs | - |
| Salazar, David | SS | Charleston Capitals | 21 | 06/11/2003 | Ames | USA | Left | Right | 5' 11" | 170 lbs | - |
| Salazar, Luis | RF | Hagerstown Sockeyes | 23 | 07/03/2001 | Teays Valley | USA | Left | Left | 6' 4" | 215 lbs | - |
| Salazar, Pedro | 1B | West Virginia Jethros | 24 | 06/28/2000 | Catia La Mar | VEN | Right | Right | 6' 6" | 205 lbs | - |
| Sanchez, Antonio | SS | Charleston Capitals | 19 | 06/29/2005 | Middleburg | USA | Right | Right | 6' 3" | 180 lbs | - |
| Sanchez, Ismael | SP | Hagerstown Sockeyes | 21 | 04/12/2003 | Boise | USA | Right | Right | 6' 6" | 200 lbs | - |
| Sanchez, Roberto | SS | Lexington Flying Eagles | 21 | 04/21/2003 | San Mateo | VEN | Right | Right | 6' 0" | 170 lbs | - |
| Sandoval, Jose | SS | Augusta Atlantics | 22 | 04/02/2002 | St. Louis | USA | Switch | Right | 6' 1" | 195 lbs | - |
| Sandoval, Norberto | RF | Greenville Emeralds | 25 | 09/14/1999 | Rockville | USA | Right | Left | 6' 4" | 205 lbs | - |
| Santos, Fernando | SP | Hickory Crazies | 22 | 12/24/2001 | Leicester | USA | Right | Right | 6' 2" | 200 lbs | - |
| Santos, Fernando | C | Asheville Bunnies | 18 | 11/07/2005 | Vicente Noble | DOM | Right | Right | 6' 1" | 190 lbs | - |
| Schultz, David | 1B | Kannapolis Gaels | 21 | 01/12/2003 | Atlanta | USA | Left | Left | 6' 5" | 210 lbs | - |
| Scott, Kel | RF | Delmarva Ratchets | 24 | 07/26/2000 | Lakewood | USA | Right | Right | 6' 0" | 190 lbs | - |
| Shepard, Dennis | RF | Greenville Emeralds | 21 | 10/31/2002 | Redding | USA | Right | Right | 6' 2" | 185 lbs | - |
| Shepherd, Daniel | RP | Kannapolis Gaels | 20 | 09/16/2004 | Yorketown | USA | Right | Right | 6' 0" | 175 lbs | - |
| Silva, Ronaldo | 2B | Hagerstown Sockeyes | 24 | 10/12/2000 | San Pedro de Macorís | DOM | Right | Right | 6' 0" | 180 lbs | - |
| Simmons, Neil | RP | West Virginia Jethros | 29 | 07/20/1995 | Rochester | USA | Left | Left | 6' 0" | 195 lbs | - |
| Singleton, Ben | CF | Greensboro Sidewinders | 23 | 11/20/2000 | Midland | USA | Right | Right | 5' 9" | 195 lbs | - |
| Smith, Chris | 3B | Lakewood Snipers | 23 | 03/11/2001 | Sandusky | USA | Right | Right | 6' 4" | 200 lbs | - |
| Smith, Ron | C | West Virginia Jethros | 20 | 02/27/2004 | Wendover | USA | Left | Right | 6' 2" | 200 lbs | - |
| Smith, Tom | SS | Savannah Sky Chiefs | 21 | 03/02/2003 | Greenville | USA | Right | Right | 6' 1" | 175 lbs | - |
| Snyder, Thomas | SS | Asheville Bunnies | 23 | 02/20/2001 | Syosset | USA | Right | Right | 6' 1" | 200 lbs | - |
| Solís, Roberto | RF | Greensboro Sidewinders | 23 | 04/21/2001 | Pink | USA | Left | Left | 5' 11" | 180 lbs | - |
| Soriano, Daniel | SP | Lexington Flying Eagles | 21 | 02/05/2003 | Guatire | VEN | Switch | Left | 6' 4" | 195 lbs | - |
| Spears, John | SP | Savannah Sky Chiefs | 24 | 08/28/2000 | Metairie | USA | Left | Left | 6' 5" | 200 lbs | - |
| Stanton, Mike | RP | Hickory Crazies | 28 | 06/23/1996 | Dublin | USA | Right | Right | 6' 4" | 205 lbs | - |
| Starr, Harold | SS | Greensboro Sidewinders | 22 | 12/29/2001 | Greensboro | USA | Right | Right | 6' 4" | 200 lbs | - |
| Stephenson, Kevin | SP | Hagerstown Sockeyes | 25 | 09/26/1999 | Ft. Bragg | USA | Right | Left | 6' 1" | 185 lbs | - |
| Stotzky, Max | RF | Hagerstown Sockeyes | 24 | 11/13/1999 | Huntington | USA | Right | Right | 6' 1" | 190 lbs | - |
| Strickland, Josh | RP | Lexington Flying Eagles | 19 | 08/26/2005 | Rancho Mirage | USA | Switch | Right | 6' 5" | 195 lbs | - |
| Sutton, Ralph | 1B | Kannapolis Gaels | 21 | 09/17/2003 | Boca Raton | USA | Right | Right | 6' 2" | 200 lbs | - |
| Swanson, Justin | RP | Charleston Capitals | 21 | 10/20/2003 | Casper | USA | Left | Right | 5' 9" | 170 lbs | - |
| Sánchez, Carlos | 3B | Hagerstown Sockeyes | 22 | 07/04/2002 | Santo Domingo | DOM | Right | Right | 6' 4" | 195 lbs | - |
| Sánchez, Gustavo | SS | Delmarva Ratchets | 22 | 12/16/2001 | Puerto Plata | DOM | Right | Right | 6' 1" | 190 lbs | - |
| Sánchez, José | RP | Rome Wild Riders | 23 | 02/19/2001 | Santo Domingo | DOM | Left | Right | 6' 9" | 205 lbs | - |
